Thermoregulation units that combine, in a single device, the direct heating of a carrier fluid (via a burner or electric resistance) and the thermoregulation of a fluid (water) to the users via a mixer or indirect system. Suitable for the thermoregulation of multiple users in the absence of an existing primary fluid network. Electronically controlled via a dedicated microprocessor system, they are equipped with a circulation pump on the secondary and primary circuits, primary circuit heating elements, expansion vessels, a power panel, a control panel, mixing units or high-efficiency exchangers, and certified control and safety systems. Available in versions for design temperatures up to 140°C and for power outputs up to 2 MW.