Thermoregulation units that use a pre-existing refrigerated fluid to thermoregulate a fluid (water) to the users via an indirect system. They are especially suitable for all those cases where it is essential to avoid contaminating the secondary fluid to the users with the primary fluid of the pre-existing line. Electronically controlled via a dedicated microprocessor system, they are equipped with a secondary circuit circulation pump, expansion vessels, a power panel, a control and management panel, high-efficiency exchanger groups, and certified control and safety systems. Available in standard versions for design temperatures from 7°C to 60°C and for power outputs up to 1 MW.